Seronegative Neuromyelitis Optica Spectrum - The challenges on disease definition and pathogenesis
Neuromyelitis optica spectrum disorders (NMOSD) are characterized by severe optic neuritis and/or longitudinally extensive transverse myelitis, and some brain lesions are also unique to NMOSD. Serum autoantibodies against aquaporin-4 (AQP4) are detected in most cases of NMOSD. However, some patients...
Main Authors: | Douglas Kazutoshi Sato, Dagoberto Callegaro, Marco Aurélio Lana-Peixoto, Ichiro Nakashima, Kazuo Fujihara |
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Format: | Article |
Language: | English |
Published: |
Academia Brasileira de Neurologia (ABNEURO)
2014-06-01
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Series: | Arquivos de Neuro-Psiquiatria |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000600445&lng=en&tlng=en |
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