The Effects of Maternal Metformin Treatment on Late Prenatal and Early Postnatal Development of the Offspring Are Modulated by Sex

The Effects of Maternal Metformin Treatment on Late Prenatal and Early Postnatal Development of the Offspring Are Modulated by Sex

Metformin is currently used to improve pregnancy outcome in women affected by polycystic ovary syndrome (PCOS) or diabetes. However, metformin may also be useful in pregnancies at risk of intrauterine growth restriction (IUGR) since it improves placental efficiency and the fetuses’ developmental com...

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Bibliographic Details
Main Authors: Consolacion Garcia-Contreras, Marta Vazquez-Gomez, José Luis Pesantez-Pacheco, Ana Heras-Molina, Teresa Encinas, Susana Astiz, Antonio Gonzalez-Bulnes
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceuticals
Subjects:
intrauterine growth restriction
metformin
pregnancy
swine model
Online Access:https://www.mdpi.com/1424-8247/13/11/363

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