Platycodigenin as Potential Drug Candidate for Alzheimer’s Disease via Modulating Microglial Polarization and Neurite Regeneration

Platycodigenin as Potential Drug Candidate for Alzheimer’s Disease via Modulating Microglial Polarization and Neurite Regeneration

Neuroinflammatory microenvironment, regulating neurite regrowth and neuronal survival, plays a critical role in Alzheimer’s disease (AD). During neuroinflammation, microglia are activated, inducing the release of inflammatory or anti-inflammatory factors depending on their polarization int...

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Bibliographic Details
Main Authors: Zhiyou Yang, Baiping Liu, Long-en Yang, Cai Zhang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
platycodigenin
microglial polarization
PPARγ
neurite regeneration
Online Access:https://www.mdpi.com/1420-3049/24/18/3207

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