Regulation of N6-Methyladenosine in the Differentiation of Cancer Stem Cells and Their Fate

Regulation of N6-Methyladenosine in the Differentiation of Cancer Stem Cells and Their Fate

N6-methyladenosine (m6A) is one of the most common internal RNA modifications in eukaryotes. It is a dynamic and reversible process that requires an orchestrated participation of methyltransferase, demethylase, and methylated binding protein. m6A modification can affect RNA degradation, translation,...

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Bibliographic Details
Main Authors: Ya Xu, Jing Liu, Wen-Jia Chen, Qian-Qian Ye, Wen-Tian Chen, Chun-Lan Li, Hua-Tao Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
m6A
stem cell
differentiation
cancer
hematopoietic
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.561703/full

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