The role of genetic polymorphisms of the VEGF, COX2, MUC genes in the development of endometriosis-associated infertility

Endometriosis-associated infertility is an important medical and social problem, because affects up to 10% of women in the reproductive case, while even after treatment the pregnancy occurs in only one third of the patients. The etiology of endometriosis is still not precisely defined, despite ongoi...

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Main Authors:	Natalia V Kulikova, Inna I Kovalenko, Dmitrii V Baibuz, Yanina A Lebedeva
Format:	Article
Language:	Russian
Published:	IP Berlin A.V. 2019-04-01
Series:	Гинекология
Subjects:	endometriosis-associated infertility mucins vascular endothelial growth factor cyclooxygenase-2 miscarriage pregnancy reproductive loss
Online Access:	https://gynecology.orscience.ru/2079-5831/article/viewFile/33471/pdf

id	doaj-1d34f9408e604d909b5b4483a55e23ce
record_format	Article
spelling	doaj-1d34f9408e604d909b5b4483a55e23ce2020-11-25T03:06:08ZrusIP Berlin A.V. Гинекология2079-56962079-58312019-04-01212343710.26442/20795696.2019.2.19034430201The role of genetic polymorphisms of the VEGF, COX2, MUC genes in the development of endometriosis-associated infertilityNatalia V Kulikova0Inna I Kovalenko1Dmitrii V Baibuz2Yanina A Lebedeva3Immanuel Kant Baltic Federal University; Saint Petersburg State UniversitySaint Petersburg State UniversitySaint Petersburg State UniversitySaint Petersburg State UniversityEndometriosis-associated infertility is an important medical and social problem, because affects up to 10% of women in the reproductive case, while even after treatment the pregnancy occurs in only one third of the patients. The etiology of endometriosis is still not precisely defined, despite ongoing research on this topic. In this review of the literature, we have tried to highlight the main work concerning the participation of immunological and genetic factors in the pathogenesis, and the role of vascular endothelial growth factor, mucins and cyclooxygenase-2 in more detail. Further studies of these pathogenetic manifestations of infertility in patients with endometriosis will make it possible to correct them in a timely manner, thereby increasing the chances of pregnancy.https://gynecology.orscience.ru/2079-5831/article/viewFile/33471/pdfendometriosis-associated infertilitymucinsvascular endothelial growth factorcyclooxygenase-2miscarriagepregnancyreproductive loss
collection	DOAJ
language	Russian
format	Article
sources	DOAJ
author	Natalia V Kulikova Inna I Kovalenko Dmitrii V Baibuz Yanina A Lebedeva
spellingShingle	Natalia V Kulikova Inna I Kovalenko Dmitrii V Baibuz Yanina A Lebedeva The role of genetic polymorphisms of the VEGF, COX2, MUC genes in the development of endometriosis-associated infertility Гинекология endometriosis-associated infertility mucins vascular endothelial growth factor cyclooxygenase-2 miscarriage pregnancy reproductive loss
author_facet	Natalia V Kulikova Inna I Kovalenko Dmitrii V Baibuz Yanina A Lebedeva
author_sort	Natalia V Kulikova
title	The role of genetic polymorphisms of the VEGF, COX2, MUC genes in the development of endometriosis-associated infertility
title_short	The role of genetic polymorphisms of the VEGF, COX2, MUC genes in the development of endometriosis-associated infertility
title_full	The role of genetic polymorphisms of the VEGF, COX2, MUC genes in the development of endometriosis-associated infertility
title_fullStr	The role of genetic polymorphisms of the VEGF, COX2, MUC genes in the development of endometriosis-associated infertility
title_full_unstemmed	The role of genetic polymorphisms of the VEGF, COX2, MUC genes in the development of endometriosis-associated infertility
title_sort	role of genetic polymorphisms of the vegf, cox2, muc genes in the development of endometriosis-associated infertility
publisher	IP Berlin A.V.
series	Гинекология
issn	2079-5696 2079-5831
publishDate	2019-04-01
description	Endometriosis-associated infertility is an important medical and social problem, because affects up to 10% of women in the reproductive case, while even after treatment the pregnancy occurs in only one third of the patients. The etiology of endometriosis is still not precisely defined, despite ongoing research on this topic. In this review of the literature, we have tried to highlight the main work concerning the participation of immunological and genetic factors in the pathogenesis, and the role of vascular endothelial growth factor, mucins and cyclooxygenase-2 in more detail. Further studies of these pathogenetic manifestations of infertility in patients with endometriosis will make it possible to correct them in a timely manner, thereby increasing the chances of pregnancy.
topic	endometriosis-associated infertility mucins vascular endothelial growth factor cyclooxygenase-2 miscarriage pregnancy reproductive loss
url	https://gynecology.orscience.ru/2079-5831/article/viewFile/33471/pdf
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The role of genetic polymorphisms of the VEGF, COX2, MUC genes in the development of endometriosis-associated infertility

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