Orofacial Granulomatosis in a Child

Orofacial Granulomatosis in a Child

Orofacial granulomatosis (OFG) is a rare, idiopathic disorder of the orofacial region. It is clinically characterized by persistent and/or recurrent enlargement of the soft tissues of the oral and maxillofacial region, often manifesting as labial enlargement and swelling of intraoral sites such as t...

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Main Authors: Reena Razdan, Maxwell D. Newby, Michele M. Carr
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2019/7519267
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spelling doaj-1d30ac9b44e84d7db618611ac50a52272020-11-24T21:23:15ZengHindawi LimitedCase Reports in Pediatrics2090-68032090-68112019-01-01201910.1155/2019/75192677519267Orofacial Granulomatosis in a ChildReena Razdan0Maxwell D. Newby1Michele M. Carr2West Virginia University School of Medicine, Morgantown, WV, USAWest Virginia University Department of Otolaryngology, Morgantown, WV, USAWest Virginia University Department of Otolaryngology, Morgantown, WV, USAOrofacial granulomatosis (OFG) is a rare, idiopathic disorder of the orofacial region. It is clinically characterized by persistent and/or recurrent enlargement of the soft tissues of the oral and maxillofacial region, often manifesting as labial enlargement and swelling of intraoral sites such as the gingiva, tongue, and buccal mucosa. Full-thickness mucosal biopsy reveals noncaseating granulomatous inflammation, similar to Crohn’s disease and sarcoidosis. Thus, OFG must be distinguished from other chronic granulomatous disorders. We report a case of a young female patient who presented with labial and maxillary gingival enlargement without any identifiable systemic causes, with suggested involvement of environmental triggers.http://dx.doi.org/10.1155/2019/7519267
collection DOAJ
language English
format Article
sources DOAJ
author Reena Razdan
Maxwell D. Newby
Michele M. Carr
spellingShingle Reena Razdan
Maxwell D. Newby
Michele M. Carr
Orofacial Granulomatosis in a Child
Case Reports in Pediatrics
author_facet Reena Razdan
Maxwell D. Newby
Michele M. Carr
author_sort Reena Razdan
title Orofacial Granulomatosis in a Child
title_short Orofacial Granulomatosis in a Child
title_full Orofacial Granulomatosis in a Child
title_fullStr Orofacial Granulomatosis in a Child
title_full_unstemmed Orofacial Granulomatosis in a Child
title_sort orofacial granulomatosis in a child
publisher Hindawi Limited
series Case Reports in Pediatrics
issn 2090-6803
2090-6811
publishDate 2019-01-01
description Orofacial granulomatosis (OFG) is a rare, idiopathic disorder of the orofacial region. It is clinically characterized by persistent and/or recurrent enlargement of the soft tissues of the oral and maxillofacial region, often manifesting as labial enlargement and swelling of intraoral sites such as the gingiva, tongue, and buccal mucosa. Full-thickness mucosal biopsy reveals noncaseating granulomatous inflammation, similar to Crohn’s disease and sarcoidosis. Thus, OFG must be distinguished from other chronic granulomatous disorders. We report a case of a young female patient who presented with labial and maxillary gingival enlargement without any identifiable systemic causes, with suggested involvement of environmental triggers.
url http://dx.doi.org/10.1155/2019/7519267
work_keys_str_mv AT reenarazdan orofacialgranulomatosisinachild
AT maxwelldnewby orofacialgranulomatosisinachild
AT michelemcarr orofacialgranulomatosisinachild
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