HCMV UL97 phosphotransferase gene mutations may be associated with antiviral resistance in immunocompromised patients in Belém, PA, Northern Brazil

HCMV UL97 phosphotransferase gene mutations may be associated with antiviral resistance in immunocompromised patients in Belém, PA, Northern Brazil

Abstract INTRODUCTION: Human cytomegalovirus is one of the causes of opportunist infections in immunocompromised patients, and is triggered by factors such as state of viral latency, weakened immune responses, and development of antiviral resistance to ganciclovir, the only drug offered by the pub...

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Main Authors: Dorotéa de Fátima Lobato da Silva, Jedson Ferreira Cardoso, Sandro Patroca da Silva, Leda Mani França Arruda, Renato Lopes Fernandes de Medeiros, Marluce Matos Moraes, Rita Catarina Medeiros Sousa
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT)
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Cytomegalovirus
Immunocompromised
Antiviral resistance
Mutations
Phosphotransferase
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200141&lng=en&tlng=en

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