Selective reduction of fat accumulation by soyasaponins A and B in high fat fed C57BL/6J mice

Soyasaponins have been shown to restrict fat absorption in the gut and reduce circulating levels of cholesterol and triacylglycerol. Most of the research in this regard have been performed using whole soyasaponins extract or soyasaponins B. In this study we aim to evaluate the effect of soyasaponins...

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Main Authors:	R.S. Govardhan Singh, Uma V. Manjappara
Format:	Article
Language:	English
Published:	Elsevier 2016-12-01
Series:	Journal of Functional Foods
Subjects:	Soyasaponins Obesity Food intake Triacylglycerol
Online Access:	http://www.sciencedirect.com/science/article/pii/S1756464616302638

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spelling	doaj-1d251d7a81794ce097e3d3e278decb502021-04-30T07:08:40ZengElsevierJournal of Functional Foods1756-46462016-12-012795103Selective reduction of fat accumulation by soyasaponins A and B in high fat fed C57BL/6J miceR.S. Govardhan Singh0Uma V. Manjappara1Department of Lipid Science, CSIR – Central Food Technological Research Institute, Mysore 570 020, IndiaCorresponding author. Department of Lipid Science, CSIR-Central Food Technological Research Institute, Mysore 570 020, India. Fax: 91-821-2517233.; Department of Lipid Science, CSIR – Central Food Technological Research Institute, Mysore 570 020, IndiaSoyasaponins have been shown to restrict fat absorption in the gut and reduce circulating levels of cholesterol and triacylglycerol. Most of the research in this regard have been performed using whole soyasaponins extract or soyasaponins B. In this study we aim to evaluate the effect of soyasaponins A and B for their ability to reduce fat depositions and plasma lipids in high fat fed C57BL/6J mice. The soyasaponins have been assayed using a previously standardized eight day treatment regimen. These experiments evaluate the immediate effects of the nutraceuticals on obesity-linked parameters. The results suggest soyasaponins A and B are equipotent and bring about similar changes in all the parameters studied.http://www.sciencedirect.com/science/article/pii/S1756464616302638SoyasaponinsObesityFood intakeTriacylglycerol
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	R.S. Govardhan Singh Uma V. Manjappara
spellingShingle	R.S. Govardhan Singh Uma V. Manjappara Selective reduction of fat accumulation by soyasaponins A and B in high fat fed C57BL/6J mice Journal of Functional Foods Soyasaponins Obesity Food intake Triacylglycerol
author_facet	R.S. Govardhan Singh Uma V. Manjappara
author_sort	R.S. Govardhan Singh
title	Selective reduction of fat accumulation by soyasaponins A and B in high fat fed C57BL/6J mice
title_short	Selective reduction of fat accumulation by soyasaponins A and B in high fat fed C57BL/6J mice
title_full	Selective reduction of fat accumulation by soyasaponins A and B in high fat fed C57BL/6J mice
title_fullStr	Selective reduction of fat accumulation by soyasaponins A and B in high fat fed C57BL/6J mice
title_full_unstemmed	Selective reduction of fat accumulation by soyasaponins A and B in high fat fed C57BL/6J mice
title_sort	selective reduction of fat accumulation by soyasaponins a and b in high fat fed c57bl/6j mice
publisher	Elsevier
series	Journal of Functional Foods
issn	1756-4646
publishDate	2016-12-01
description	Soyasaponins have been shown to restrict fat absorption in the gut and reduce circulating levels of cholesterol and triacylglycerol. Most of the research in this regard have been performed using whole soyasaponins extract or soyasaponins B. In this study we aim to evaluate the effect of soyasaponins A and B for their ability to reduce fat depositions and plasma lipids in high fat fed C57BL/6J mice. The soyasaponins have been assayed using a previously standardized eight day treatment regimen. These experiments evaluate the immediate effects of the nutraceuticals on obesity-linked parameters. The results suggest soyasaponins A and B are equipotent and bring about similar changes in all the parameters studied.
topic	Soyasaponins Obesity Food intake Triacylglycerol
url	http://www.sciencedirect.com/science/article/pii/S1756464616302638
work_keys_str_mv	AT rsgovardhansingh selectivereductionoffataccumulationbysoyasaponinsaandbinhighfatfedc57bl6jmice AT umavmanjappara selectivereductionoffataccumulationbysoyasaponinsaandbinhighfatfedc57bl6jmice
_version_	1721499609408208896

Selective reduction of fat accumulation by soyasaponins A and B in high fat fed C57BL/6J mice

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