Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans.

Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans.

BACKGROUND: Podocytes are highly specialized epithelial cells on the visceral side of the glomerulus. Their interdigitating primary and secondary foot processes contain an actin based contractile apparatus that can adjust to changes in the glomerular perfusion pressure. Thus, the dynamic regulation...

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Main Authors: Sharon Ashworth, Beina Teng, Jessica Kaufeld, Emily Miller, Irini Tossidou, Christoph Englert, Frank Bollig, Lynne Staggs, Ian S D Roberts, Joon-Keun Park, Hermann Haller, Mario Schiffer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2935884?pdf=render

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http://europepmc.org/articles/PMC2935884?pdf=render

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