Apoptosis Induction of Human Prostate Carcinoma DU145 Cells by Diallyl Disulfide via Modulation of JNK and PI3K/AKT Signaling Pathways

Apoptosis Induction of Human Prostate Carcinoma DU145 Cells by Diallyl Disulfide via Modulation of JNK and PI3K/AKT Signaling Pathways

Diallyl disulfide (DADS), a sulfur compound derived from garlic, has various biological properties, such as anticancer, antiangiogenic and anti-inflammatory effects. However, the mechanisms of action underlying the compound's anticancer activity have not been fully elucidated. In this study...

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Bibliographic Details
Main Authors: Young Hyun Yoo, Byung Tae Choi, Jun Hyuk Lee, Gi-Young Kim, Dong Yeok Shin, Yung Hyun Choi
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:International Journal of Molecular Sciences
Subjects:
diallyl disulfide
apoptosis
MAPK
PI3K/Akt
Online Access:http://www.mdpi.com/1422-0067/13/11/14158

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