Cross-presentation of cell-associated antigens by MHC class I in dendritic cell subsets

Cross-presentation of cell-associated antigens by MHC class I in dendritic cell subsets

Dendritic cells have the unique ability to pick up dead cells carrying antigens in tissue and migrate to the lymph nodes where they can cross-present cell-associated antigens by MHC class I to CD8+ T cells. There is strong in vivo evidence that the mouse XCR1+ dendritic cells subset acts as a key pl...

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Bibliographic Details
Main Authors: Enric eGutiérrez-Martínez, Remi ePlanès, Giorgio eAnselmi, Matthew eReynolds, Shinelle eMenezes, Adiko Assi Aimé Cézaire, Loredana eSaveanu, Pierre eGuermonprez
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Immunology
Subjects:
Cross-Priming
Dendritic Cells
Phagocytosis
MHC class I
antigen processing
cross-presentation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00363/full

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