Immunomodulation of carcinogens-induced steroids-dependent human diseases

Immunomodulation of carcinogens-induced steroids-dependent human diseases

The experimental and clinical data about antibodies against environmental chemical carcinogens and endogenous steroids are represented. The conception of immunomodulation of carcinogens- and steroids-dependent human diseases is proposed. It is postulated that antibodies to polycyclic aromatic hydroc...

Full description

Bibliographic Details
Main Authors: Andrew N. Glushkov, Elena G. Polenok
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Saudi Journal of Biological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X1730236X
id doaj-1cf959b385a74595aebf5dff478686c1
record_format Article
spelling doaj-1cf959b385a74595aebf5dff478686c12020-11-25T02:15:23ZengElsevierSaudi Journal of Biological Sciences1319-562X2019-02-01262244251Immunomodulation of carcinogens-induced steroids-dependent human diseasesAndrew N. Glushkov0Elena G. Polenok1Institute of Human Ecology, Federal Research Center of Coal and Coal Chemistry of Siberian Branch of the Russian Academy of Sciences, Kemerovo 650065, Russian FederationCorresponding author.; Institute of Human Ecology, Federal Research Center of Coal and Coal Chemistry of Siberian Branch of the Russian Academy of Sciences, Kemerovo 650065, Russian FederationThe experimental and clinical data about antibodies against environmental chemical carcinogens and endogenous steroids are represented. The conception of immunomodulation of carcinogens- and steroids-dependent human diseases is proposed. It is postulated that antibodies to polycyclic aromatic hydrocarbons and heterocyclic amines in cooperation with antibodies to cholesterol, sex hormones, mineralo- and glucocorticoids stimulate or inhibit cancer, malformation, cardiovascular and autoimmune diseases depending on their personal combination. It is recommended to use immunoassay of these antibodies for the human diseases prediction. The alternative approaches for prevention using the probiotics transformed by anti-carcinogen antibodies are substantiated. Keywords: Antibody formation, Benzo[a]pyrene, Cholesterol, Estradiol, Progesterone, Prediction, Preventionhttp://www.sciencedirect.com/science/article/pii/S1319562X1730236X
collection DOAJ
language English
format Article
sources DOAJ
author Andrew N. Glushkov
Elena G. Polenok
spellingShingle Andrew N. Glushkov
Elena G. Polenok
Immunomodulation of carcinogens-induced steroids-dependent human diseases
Saudi Journal of Biological Sciences
author_facet Andrew N. Glushkov
Elena G. Polenok
author_sort Andrew N. Glushkov
title Immunomodulation of carcinogens-induced steroids-dependent human diseases
title_short Immunomodulation of carcinogens-induced steroids-dependent human diseases
title_full Immunomodulation of carcinogens-induced steroids-dependent human diseases
title_fullStr Immunomodulation of carcinogens-induced steroids-dependent human diseases
title_full_unstemmed Immunomodulation of carcinogens-induced steroids-dependent human diseases
title_sort immunomodulation of carcinogens-induced steroids-dependent human diseases
publisher Elsevier
series Saudi Journal of Biological Sciences
issn 1319-562X
publishDate 2019-02-01
description The experimental and clinical data about antibodies against environmental chemical carcinogens and endogenous steroids are represented. The conception of immunomodulation of carcinogens- and steroids-dependent human diseases is proposed. It is postulated that antibodies to polycyclic aromatic hydrocarbons and heterocyclic amines in cooperation with antibodies to cholesterol, sex hormones, mineralo- and glucocorticoids stimulate or inhibit cancer, malformation, cardiovascular and autoimmune diseases depending on their personal combination. It is recommended to use immunoassay of these antibodies for the human diseases prediction. The alternative approaches for prevention using the probiotics transformed by anti-carcinogen antibodies are substantiated. Keywords: Antibody formation, Benzo[a]pyrene, Cholesterol, Estradiol, Progesterone, Prediction, Prevention
url http://www.sciencedirect.com/science/article/pii/S1319562X1730236X
work_keys_str_mv AT andrewnglushkov immunomodulationofcarcinogensinducedsteroidsdependenthumandiseases
AT elenagpolenok immunomodulationofcarcinogensinducedsteroidsdependenthumandiseases
_version_ 1724896811358879744

Similar Items