Dose-Dependent Neuroprotective Effect of Standardized Bee Venom Phospholipase A2 Against MPTP-Induced Parkinson’s Disease in Mice

Dose-Dependent Neuroprotective Effect of Standardized Bee Venom Phospholipase A2 Against MPTP-Induced Parkinson’s Disease in Mice

Parkinson’s disease (PD) is a chronic progressive neurodegenerative movement disorder characterized by the selective loss of dopaminergic neurons within the substantia nigra (SN). While the precise etiology of dopaminergic neuronal demise is elusive, multiple lines of evidence indicate that neuroinf...

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Bibliographic Details
Main Authors: Kyung Hwa Kim, Seung Young Lee, Jaekwon Shin, Jae-Taeg Hwang, Hat Nim Jeon, Hyunsu Bae
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson’s disease
regulatory T cells
bee venom phospholipase A2
neuroinflammation
dose-dependent response
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00080/full

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