Development of acute dystonia in three brothers due to metoclopramide

• Main Authors: Ibrahim Silfeler, Vefik Arica, Secil Arica, Murat Dogan
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2012-01-01
• Series: Journal of Research in Medical Sciences
• Subjects: Dystonic reaction; medicine side effects; metoclopramide
• Online Access: http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2012;volume=17;issue=3;spage=308;epage=309;aulast=Silfeler

One of the agents that cause dystonic reactions is metoclopramide. In this study, we presented three individuals of the same family who were admitted to our hospital while receiving the treatment of metoclopramide because of developing acute dystonic reaction. Appropriate doses of metoclopramide therapy had begun to all brothers with a diagnosis of gastroenteritis. After receiving the first dose of medication, acute dystonia was observed within half an hour in these brothers who used metoclopramide. Thus, if there is a patient who developed acute dystonia in the same family due to metoclopramide, avoiding from use of metoclopramide will be beneficial for other members of the family.