Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression

Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression

Metastasis is the cause of more than 90% of all cancer deaths. Despite this fact, most anticancer therapeutics currently in clinical use have limited efficacy in treating established metastases. Here, we identify the endoplasmic reticulum chaperone protein, glucose-regulated protein 78 (GRP78), as a...

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Bibliographic Details
Main Authors: Michael M. Lizardo, James J. Morrow, Tyler E. Miller, Ellen S. Hong, Ling Ren, Arnulfo Mendoza, Charles H. Halsey, Peter C. Scacheri, Lee J. Helman, Chand Khanna
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558616300501

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http://www.sciencedirect.com/science/article/pii/S1476558616300501

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