Features of the use of torasemide in arterial hypertension

• Main Authors: Baryshnikova G.A., Chorbinskaya S.A.
• Format: Article
• Language: Russian
• Published: IP Morozov P.V. 2017-11-01
• Series: Системные гипертензии
• Subjects: arterial hypertension; treatment of arterial hypertension; antihypertensive therapy; diuretics; thiazide diuretics; loop diuretics; torasemide; antialdosterone effect; antifibrotic effect; metabolic neutrality.; metabolic neutrality
• Online Access: http://syst-hypertension.ru/en/archive/2017/vol-14-4-2017/features-of-the-use-of-torasemide-in-arterial-hypertension_1824/
• ISSN: 2075-082X; 2542-2189

The article deals with the choice of diuretic in arterial hypertension and presents data on the antihypertensive efficacy of the loop diuretic torasemide. Data on the mechanisms of antihypertensive action of torasemide are presented, including a unique antialdosterone effect. The article reports on the absence of a negative effect of the drug on carbohydrate, lipid, purine metabolism and electrolyte balance, positive effect on the target organs, very good tolerability. It is advisable to use torasemide more widely in a "non-diuretic" dose (2.5-5 mg / day) for the treatment of arterial hypertension as in monotherapy as in combination with other antihypertensive drugs.