Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer

Abstract In addition to its implication in hereditary hearing loss, the Gasdermin E (GSDME) gene is also a tumor suppressor involved in cancer progression through programmed cell death. GSDME epigenetic silencing through methylation has been shown in some cancer types, but studies are yet to fully e...

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Bibliographic Details
Main Authors: Joe Ibrahim, Ken Op de Beeck, Erik Fransen, Lieselot Croes, Matthias Beyens, Arvid Suls, Wim Vanden Berghe, Marc Peeters, Guy Van Camp
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.2103