Strains of Rodents and the Pharmacology of Learning and Memory

Strains of Rodents and the Pharmacology of Learning and Memory

Mendelian genetic tools have extensively been used to improve the description of the pharmacological mechanisms involved in learning and memory. The first part of this short review describes experiments involving the bidirectional selection of rats or mice for extreme behavioral characteristics or f...

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Main Authors: Martine Ammassari-Teule, Claudio Castellano
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/NP.2004.205
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spelling doaj-1cc07129c80d4282a81b370af1661b172020-11-24T23:21:55ZengHindawi LimitedNeural Plasticity2090-59041687-54432004-01-01113-420521610.1155/NP.2004.205Strains of Rodents and the Pharmacology of Learning and MemoryMartine Ammassari-Teule0Claudio Castellano1CNR Institute of Neuroscience, Laboratory of Psychobiology and Psychopharmacology, Rome, ItalyCNR Institute of Neuroscience, Laboratory of Psychobiology and Psychopharmacology, Rome, ItalyMendelian genetic tools have extensively been used to improve the description of the pharmacological mechanisms involved in learning and memory. The first part of this short review describes experiments involving the bidirectional selection of rats or mice for extreme behavioral characteristics or for sensitivity to pharmacological treatments. The second part focuses specifically on inbreeding. In conclusion, the advantages and the limits of a Mendelian pharmacogenetic approach of learning and memory are discussed.http://dx.doi.org/10.1155/NP.2004.205
collection DOAJ
language English
format Article
sources DOAJ
author Martine Ammassari-Teule
Claudio Castellano
spellingShingle Martine Ammassari-Teule
Claudio Castellano
Strains of Rodents and the Pharmacology of Learning and Memory
Neural Plasticity
author_facet Martine Ammassari-Teule
Claudio Castellano
author_sort Martine Ammassari-Teule
title Strains of Rodents and the Pharmacology of Learning and Memory
title_short Strains of Rodents and the Pharmacology of Learning and Memory
title_full Strains of Rodents and the Pharmacology of Learning and Memory
title_fullStr Strains of Rodents and the Pharmacology of Learning and Memory
title_full_unstemmed Strains of Rodents and the Pharmacology of Learning and Memory
title_sort strains of rodents and the pharmacology of learning and memory
publisher Hindawi Limited
series Neural Plasticity
issn 2090-5904
1687-5443
publishDate 2004-01-01
description Mendelian genetic tools have extensively been used to improve the description of the pharmacological mechanisms involved in learning and memory. The first part of this short review describes experiments involving the bidirectional selection of rats or mice for extreme behavioral characteristics or for sensitivity to pharmacological treatments. The second part focuses specifically on inbreeding. In conclusion, the advantages and the limits of a Mendelian pharmacogenetic approach of learning and memory are discussed.
url http://dx.doi.org/10.1155/NP.2004.205
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AT claudiocastellano strainsofrodentsandthepharmacologyoflearningandmemory
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