Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy
Acute oxalate nephropathy (AON) is an increasingly recognized cause of acute kidney injury (AKI). Herein, we present two cases of biopsy-proven acute oxalate nephropathy in patients with gastrointestinal malabsorption, coincidentally both stemming from cholangiocarcinoma. The first is a 73-year-old...
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Hindawi Limited
2018-01-01
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Series: | Case Reports in Nephrology |
Online Access: | http://dx.doi.org/10.1155/2018/8641893 |
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doaj-1cb74694330947299bb1ceb877af4b762020-11-25T00:45:52ZengHindawi LimitedCase Reports in Nephrology2090-66412090-665X2018-01-01201810.1155/2018/86418938641893Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate NephropathyBenjamin Fox0Nishkarsh Saxena1Leah Schuppener2Laura Maursetter3University of Wisconsin School of Medicine and Public Health, Madison Wisconsin, USASouthwest Kidney Specialists, University of Wisconsin School of Medicine and Public Health, Madison, WI, USADivision of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USADivision of Nephrology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USAAcute oxalate nephropathy (AON) is an increasingly recognized cause of acute kidney injury (AKI). Herein, we present two cases of biopsy-proven acute oxalate nephropathy in patients with gastrointestinal malabsorption, coincidentally both stemming from cholangiocarcinoma. The first is a 73-year-old male who presented with syncope and was found to have severe, oliguric AKI in the setting of newly diagnosed, nonresectable cholangiocarcinoma. The second is a 64-year-old man with remote resection of cholangiocarcinoma who presented after routine laboratory monitoring showed significant AKI. Temporary dialysis was required in both cases before renal recovery occurred. Together, these cases should increase physicians’ suspicion of AON in the presence of malabsorption. By doing so, the workup of oxalate nephropathy can be expedited with prompt initiation of treatment.http://dx.doi.org/10.1155/2018/8641893 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Benjamin Fox Nishkarsh Saxena Leah Schuppener Laura Maursetter |
spellingShingle |
Benjamin Fox Nishkarsh Saxena Leah Schuppener Laura Maursetter Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy Case Reports in Nephrology |
author_facet |
Benjamin Fox Nishkarsh Saxena Leah Schuppener Laura Maursetter |
author_sort |
Benjamin Fox |
title |
Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy |
title_short |
Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy |
title_full |
Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy |
title_fullStr |
Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy |
title_full_unstemmed |
Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy |
title_sort |
combining acute kidney injury with gastrointestinal pathology: a clue to acute oxalate nephropathy |
publisher |
Hindawi Limited |
series |
Case Reports in Nephrology |
issn |
2090-6641 2090-665X |
publishDate |
2018-01-01 |
description |
Acute oxalate nephropathy (AON) is an increasingly recognized cause of acute kidney injury (AKI). Herein, we present two cases of biopsy-proven acute oxalate nephropathy in patients with gastrointestinal malabsorption, coincidentally both stemming from cholangiocarcinoma. The first is a 73-year-old male who presented with syncope and was found to have severe, oliguric AKI in the setting of newly diagnosed, nonresectable cholangiocarcinoma. The second is a 64-year-old man with remote resection of cholangiocarcinoma who presented after routine laboratory monitoring showed significant AKI. Temporary dialysis was required in both cases before renal recovery occurred. Together, these cases should increase physicians’ suspicion of AON in the presence of malabsorption. By doing so, the workup of oxalate nephropathy can be expedited with prompt initiation of treatment. |
url |
http://dx.doi.org/10.1155/2018/8641893 |
work_keys_str_mv |
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