Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy

Acute oxalate nephropathy (AON) is an increasingly recognized cause of acute kidney injury (AKI). Herein, we present two cases of biopsy-proven acute oxalate nephropathy in patients with gastrointestinal malabsorption, coincidentally both stemming from cholangiocarcinoma. The first is a 73-year-old...

Full description

Bibliographic Details
Main Authors: Benjamin Fox, Nishkarsh Saxena, Leah Schuppener, Laura Maursetter
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2018/8641893
id doaj-1cb74694330947299bb1ceb877af4b76
record_format Article
spelling doaj-1cb74694330947299bb1ceb877af4b762020-11-25T00:45:52ZengHindawi LimitedCase Reports in Nephrology2090-66412090-665X2018-01-01201810.1155/2018/86418938641893Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate NephropathyBenjamin Fox0Nishkarsh Saxena1Leah Schuppener2Laura Maursetter3University of Wisconsin School of Medicine and Public Health, Madison Wisconsin, USASouthwest Kidney Specialists, University of Wisconsin School of Medicine and Public Health, Madison, WI, USADivision of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USADivision of Nephrology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USAAcute oxalate nephropathy (AON) is an increasingly recognized cause of acute kidney injury (AKI). Herein, we present two cases of biopsy-proven acute oxalate nephropathy in patients with gastrointestinal malabsorption, coincidentally both stemming from cholangiocarcinoma. The first is a 73-year-old male who presented with syncope and was found to have severe, oliguric AKI in the setting of newly diagnosed, nonresectable cholangiocarcinoma. The second is a 64-year-old man with remote resection of cholangiocarcinoma who presented after routine laboratory monitoring showed significant AKI. Temporary dialysis was required in both cases before renal recovery occurred. Together, these cases should increase physicians’ suspicion of AON in the presence of malabsorption. By doing so, the workup of oxalate nephropathy can be expedited with prompt initiation of treatment.http://dx.doi.org/10.1155/2018/8641893
collection DOAJ
language English
format Article
sources DOAJ
author Benjamin Fox
Nishkarsh Saxena
Leah Schuppener
Laura Maursetter
spellingShingle Benjamin Fox
Nishkarsh Saxena
Leah Schuppener
Laura Maursetter
Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy
Case Reports in Nephrology
author_facet Benjamin Fox
Nishkarsh Saxena
Leah Schuppener
Laura Maursetter
author_sort Benjamin Fox
title Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy
title_short Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy
title_full Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy
title_fullStr Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy
title_full_unstemmed Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy
title_sort combining acute kidney injury with gastrointestinal pathology: a clue to acute oxalate nephropathy
publisher Hindawi Limited
series Case Reports in Nephrology
issn 2090-6641
2090-665X
publishDate 2018-01-01
description Acute oxalate nephropathy (AON) is an increasingly recognized cause of acute kidney injury (AKI). Herein, we present two cases of biopsy-proven acute oxalate nephropathy in patients with gastrointestinal malabsorption, coincidentally both stemming from cholangiocarcinoma. The first is a 73-year-old male who presented with syncope and was found to have severe, oliguric AKI in the setting of newly diagnosed, nonresectable cholangiocarcinoma. The second is a 64-year-old man with remote resection of cholangiocarcinoma who presented after routine laboratory monitoring showed significant AKI. Temporary dialysis was required in both cases before renal recovery occurred. Together, these cases should increase physicians’ suspicion of AON in the presence of malabsorption. By doing so, the workup of oxalate nephropathy can be expedited with prompt initiation of treatment.
url http://dx.doi.org/10.1155/2018/8641893
work_keys_str_mv AT benjaminfox combiningacutekidneyinjurywithgastrointestinalpathologyacluetoacuteoxalatenephropathy
AT nishkarshsaxena combiningacutekidneyinjurywithgastrointestinalpathologyacluetoacuteoxalatenephropathy
AT leahschuppener combiningacutekidneyinjurywithgastrointestinalpathologyacluetoacuteoxalatenephropathy
AT lauramaursetter combiningacutekidneyinjurywithgastrointestinalpathologyacluetoacuteoxalatenephropathy
_version_ 1725268311529226240