Autocrine production of reproductive axis neuropeptides affects proliferation of canine osteosarcoma in vitro

Autocrine production of reproductive axis neuropeptides affects proliferation of canine osteosarcoma in vitro

Abstract Background Osteosarcoma strikes hundreds of people each year, of both advanced and younger ages, and is often terminal. Like many tumor types, these bone tumors will frequently undergo a neuroendocrine transition, utilizing autocrine and/or paracrine hormones as growth factors and/or promot...

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Bibliographic Details
Main Authors: Marcus A. Weinman, Jacob A. Fischer, Dakota C. Jacobs, Cheri P. Goodall, Shay Bracha, Patrick E. Chappell
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Cancer
Subjects:
Osteosarcoma
GnRH
Kisspeptin
Autocrine
Proliferation
Online Access:http://link.springer.com/article/10.1186/s12885-019-5363-4

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http://link.springer.com/article/10.1186/s12885-019-5363-4

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