Current concepts regarding the HTLV-1 receptor complex
<p>Abstract</p> <p>The identity of the Human T lymphotropic Virus type 1 (HTLV-1) receptor remained an unsolved puzzle for two decades, until the recent demonstration that three molecules, Glucose Transporter 1, Neuropilin-1 and Heparan Sulfate Proteoglycans are involved in HTLV-1...
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doaj-1c9aa3ecc15042f4ac2ae9bbe534f4ef2020-11-24T20:44:15ZengBMCRetrovirology1742-46902010-11-01719910.1186/1742-4690-7-99Current concepts regarding the HTLV-1 receptor complexJones Kathryn SLepelletier YvesGhez DavidPique ClaudineHermine Olivier<p>Abstract</p> <p>The identity of the Human T lymphotropic Virus type 1 (HTLV-1) receptor remained an unsolved puzzle for two decades, until the recent demonstration that three molecules, Glucose Transporter 1, Neuropilin-1 and Heparan Sulfate Proteoglycans are involved in HTLV-1 binding and entry. Despite these advances, several questions remain unanswered, including the precise role of each of these molecules during virus entry. In light of the most recent data, we propose a model of the HTLV-1 receptor complex and discuss its potential impact on HTLV-1 infection.</p> http://www.retrovirology.com/content/7/1/99 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jones Kathryn S Lepelletier Yves Ghez David Pique Claudine Hermine Olivier |
spellingShingle |
Jones Kathryn S Lepelletier Yves Ghez David Pique Claudine Hermine Olivier Current concepts regarding the HTLV-1 receptor complex Retrovirology |
author_facet |
Jones Kathryn S Lepelletier Yves Ghez David Pique Claudine Hermine Olivier |
author_sort |
Jones Kathryn S |
title |
Current concepts regarding the HTLV-1 receptor complex |
title_short |
Current concepts regarding the HTLV-1 receptor complex |
title_full |
Current concepts regarding the HTLV-1 receptor complex |
title_fullStr |
Current concepts regarding the HTLV-1 receptor complex |
title_full_unstemmed |
Current concepts regarding the HTLV-1 receptor complex |
title_sort |
current concepts regarding the htlv-1 receptor complex |
publisher |
BMC |
series |
Retrovirology |
issn |
1742-4690 |
publishDate |
2010-11-01 |
description |
<p>Abstract</p> <p>The identity of the Human T lymphotropic Virus type 1 (HTLV-1) receptor remained an unsolved puzzle for two decades, until the recent demonstration that three molecules, Glucose Transporter 1, Neuropilin-1 and Heparan Sulfate Proteoglycans are involved in HTLV-1 binding and entry. Despite these advances, several questions remain unanswered, including the precise role of each of these molecules during virus entry. In light of the most recent data, we propose a model of the HTLV-1 receptor complex and discuss its potential impact on HTLV-1 infection.</p> |
url |
http://www.retrovirology.com/content/7/1/99 |
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