The core binding factor CBF negatively regulates skeletal muscle terminal differentiation.

The core binding factor CBF negatively regulates skeletal muscle terminal differentiation.

BACKGROUND: Core Binding Factor or CBF is a transcription factor composed of two subunits, Runx1/AML-1 and CBF beta or CBFbeta. CBF was originally described as a regulator of hematopoiesis. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that CBF is involved in the control of skeletal muscle terminal d...

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Bibliographic Details
Main Authors: Ophélie Philipot, Véronique Joliot, Ouardia Ait-Mohamed, Céline Pellentz, Philippe Robin, Lauriane Fritsch, Slimane Ait-Si-Ali
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2828485?pdf=render

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