"Targeted disruption of the epithelial-barrier by <it>Helicobacter pylori</it>"
<p>Abstract</p> <p><it>Helicobacter pylori </it>colonizes the human gastric epithelium and induces chronic gastritis, which can lead to gastric cancer. Through cell-cell contacts the gastric epithelium forms a barrier to protect underlying tissue from pathogenic bacteri...
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| Format: | Article |
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BMC
2011-11-01
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| Series: | Cell Communication and Signaling |
| Online Access: | http://www.biosignaling.com/content/9/1/29 |
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doaj-1c937bf95cf34e99ba06c3a9bf77faec2020-11-24T21:24:43ZengBMCCell Communication and Signaling1478-811X2011-11-01912910.1186/1478-811X-9-29"Targeted disruption of the epithelial-barrier by <it>Helicobacter pylori</it>"Wroblewski Lydia EPeek Richard M<p>Abstract</p> <p><it>Helicobacter pylori </it>colonizes the human gastric epithelium and induces chronic gastritis, which can lead to gastric cancer. Through cell-cell contacts the gastric epithelium forms a barrier to protect underlying tissue from pathogenic bacteria; however, <it>H. pylori </it>have evolved numerous strategies to perturb the integrity of the gastric barrier. In this review, we summarize recent research into the mechanisms through which <it>H. pylori </it>disrupts intercellular junctions and disrupts the gastric epithelial barrier.</p> http://www.biosignaling.com/content/9/1/29 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Wroblewski Lydia E Peek Richard M |
| spellingShingle |
Wroblewski Lydia E Peek Richard M "Targeted disruption of the epithelial-barrier by <it>Helicobacter pylori</it>" Cell Communication and Signaling |
| author_facet |
Wroblewski Lydia E Peek Richard M |
| author_sort |
Wroblewski Lydia E |
| title |
"Targeted disruption of the epithelial-barrier by <it>Helicobacter pylori</it>" |
| title_short |
"Targeted disruption of the epithelial-barrier by <it>Helicobacter pylori</it>" |
| title_full |
"Targeted disruption of the epithelial-barrier by <it>Helicobacter pylori</it>" |
| title_fullStr |
"Targeted disruption of the epithelial-barrier by <it>Helicobacter pylori</it>" |
| title_full_unstemmed |
"Targeted disruption of the epithelial-barrier by <it>Helicobacter pylori</it>" |
| title_sort |
"targeted disruption of the epithelial-barrier by <it>helicobacter pylori</it>" |
| publisher |
BMC |
| series |
Cell Communication and Signaling |
| issn |
1478-811X |
| publishDate |
2011-11-01 |
| description |
<p>Abstract</p> <p><it>Helicobacter pylori </it>colonizes the human gastric epithelium and induces chronic gastritis, which can lead to gastric cancer. Through cell-cell contacts the gastric epithelium forms a barrier to protect underlying tissue from pathogenic bacteria; however, <it>H. pylori </it>have evolved numerous strategies to perturb the integrity of the gastric barrier. In this review, we summarize recent research into the mechanisms through which <it>H. pylori </it>disrupts intercellular junctions and disrupts the gastric epithelial barrier.</p> |
| url |
http://www.biosignaling.com/content/9/1/29 |
| work_keys_str_mv |
AT wroblewskilydiae targeteddisruptionoftheepithelialbarrierbyithelicobacterpyloriit AT peekrichardm targeteddisruptionoftheepithelialbarrierbyithelicobacterpyloriit |
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1725986451173146624 |