ALDH7A1 inhibits the intracellular transport pathways during hypoxia and starvation to promote cellular energy homeostasis
Intracellular vesicle transport can be regulated by Brefeldin‐A ADP‐Ribosylated Substrate (BARS) during vesicle fission. Here, the authors show that NADH generated by aldehyde dehydrogenase 7A1 (ALDH7A1) inhibits intracellular transport by targeting BARS and inhibiting COPI vesicle fission during si...
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Bibliographic Details
| Main Authors: |
Jia-Shu Yang,
Jia-Wei Hsu,
Seung-Yeol Park,
Stella Y. Lee,
Jian Li,
Ming Bai,
Claudia Alves,
William Tseng,
Xavier Michelet,
I-Cheng Ho,
Victor W. Hsu |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2019-09-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-11932-0
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