HILIC-MS rat brain analysis, a new approach for the study of ischemic attack

HILIC-MS rat brain analysis, a new approach for the study of ischemic attack

Clinicians often rely on selected small molecular compounds from body fluids for the detection, screening or monitoring of numerous life-threatening diseases. Among others, important monoamines – biogenic amines (BAs) – and their metabolites serve as sensitive biomarkers to study the progression or...

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Main Authors: Miękus Natalia, Konieczna Lucyna, Kowiański Przemysław, Moryś Janusz, Bączek Tomasz
Format: Article
Language:English
Published: De Gruyter 2017-08-01
Series:Translational Neuroscience
Subjects:
high-performance analytical method
transient ischemic attack
sample preparation
neurotransmitters
biogenic amines
Online Access:https://doi.org/10.1515/tnsci-2017-0012
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spelling doaj-1c76b0df2d614f2e91759d8cabf1e0d32021-09-05T20:51:30ZengDe GruyterTranslational Neuroscience2081-69362017-08-0181707510.1515/tnsci-2017-0012tnsci-2017-0012HILIC-MS rat brain analysis, a new approach for the study of ischemic attackMiękus Natalia0Konieczna Lucyna1Kowiański Przemysław2Moryś Janusz3Bączek Tomasz4Department of Animal and Human Physiology, University of Gdańsk, Wita Stwosza 59, 80-308Gdańsk, PolandDepartment of Pharmaceutical Chemistry, Medical University of Gdańsk, Gen. J. Hallera 107, 80-416Gdańsk, PolandDepartment of Anatomy and Neurobiology, Medical University of Gdańsk, Dębinki 1, 80-211Gdańsk, PolandDepartment of Anatomy and Neurobiology, Medical University of Gdańsk, Dębinki 1, 80-211Gdańsk, PolandDepartment of Pharmaceutical Chemistry, Medical University of Gdańsk, Gen. J. Hallera 107, 80-416Gdańsk, PolandClinicians often rely on selected small molecular compounds from body fluids for the detection, screening or monitoring of numerous life-threatening diseases. Among others, important monoamines – biogenic amines (BAs) – and their metabolites serve as sensitive biomarkers to study the progression or even early detection of on-going brain pathologies or tumors of neuroendocrine origins. Undertaking the task to optimize a reliable method for the simultaneous analysis of the most relevant BAs in biological matrices is of utmost importance for scientists.https://doi.org/10.1515/tnsci-2017-0012high-performance analytical methodtransient ischemic attacksample preparationneurotransmittersbiogenic amines
collection DOAJ
language English
format Article
sources DOAJ
author Miękus Natalia
Konieczna Lucyna
Kowiański Przemysław
Moryś Janusz
Bączek Tomasz
spellingShingle Miękus Natalia
Konieczna Lucyna
Kowiański Przemysław
Moryś Janusz
Bączek Tomasz
HILIC-MS rat brain analysis, a new approach for the study of ischemic attack
Translational Neuroscience
high-performance analytical method
transient ischemic attack
sample preparation
neurotransmitters
biogenic amines
author_facet Miękus Natalia
Konieczna Lucyna
Kowiański Przemysław
Moryś Janusz
Bączek Tomasz
author_sort Miękus Natalia
title HILIC-MS rat brain analysis, a new approach for the study of ischemic attack
title_short HILIC-MS rat brain analysis, a new approach for the study of ischemic attack
title_full HILIC-MS rat brain analysis, a new approach for the study of ischemic attack
title_fullStr HILIC-MS rat brain analysis, a new approach for the study of ischemic attack
title_full_unstemmed HILIC-MS rat brain analysis, a new approach for the study of ischemic attack
title_sort hilic-ms rat brain analysis, a new approach for the study of ischemic attack
publisher De Gruyter
series Translational Neuroscience
issn 2081-6936
publishDate 2017-08-01
description Clinicians often rely on selected small molecular compounds from body fluids for the detection, screening or monitoring of numerous life-threatening diseases. Among others, important monoamines – biogenic amines (BAs) – and their metabolites serve as sensitive biomarkers to study the progression or even early detection of on-going brain pathologies or tumors of neuroendocrine origins. Undertaking the task to optimize a reliable method for the simultaneous analysis of the most relevant BAs in biological matrices is of utmost importance for scientists.
topic high-performance analytical method
transient ischemic attack
sample preparation
neurotransmitters
biogenic amines
url https://doi.org/10.1515/tnsci-2017-0012
work_keys_str_mv AT miekusnatalia hilicmsratbrainanalysisanewapproachforthestudyofischemicattack
AT koniecznalucyna hilicmsratbrainanalysisanewapproachforthestudyofischemicattack
AT kowianskiprzemysław hilicmsratbrainanalysisanewapproachforthestudyofischemicattack
AT morysjanusz hilicmsratbrainanalysisanewapproachforthestudyofischemicattack
AT baczektomasz hilicmsratbrainanalysisanewapproachforthestudyofischemicattack
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