The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus

The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus

Objectives. The present study was designed to assess whether apoptosis-related genes as parp-1 and bax could be targets for treatment of diabetes mellitus and whether vitamin D may exert beneficial effects.

Bibliographic Details
Main Authors: Kuchmerovska Tamara, Guzyk Mykhailo, Tykhonenko Tetiana, Yanitska Lesya, Pryvrotska Irina, Diakun Kateryna
Format: Article
Language:English
Published: Sciendo 2021-04-01
Series:Endocrine Regulations
Subjects:
type 1 diabetes mellitus
mrna expression
parp-1 gene
bax gene
vitamin d3
Online Access:https://doi.org/10.2478/enr-2021-0008
id doaj-1c73dcfeb99a4c29b8491d53db56ff95
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spelling doaj-1c73dcfeb99a4c29b8491d53db56ff952021-09-05T21:00:49ZengSciendoEndocrine Regulations1336-03292021-04-01552617110.2478/enr-2021-0008The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitusKuchmerovska Tamara0Guzyk Mykhailo1Tykhonenko Tetiana2Yanitska Lesya3Pryvrotska Irina4Diakun Kateryna5Department of Vitamin and Coenzyme Biochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, UkraineDepartment of Vitamin and Coenzyme Biochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, UkraineDepartment of Vitamin and Coenzyme Biochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, UkraineBogomolets National Medical University, Kyiv, UkraineHorbachevsky Ternopil State Medical University, Ministry of Public Health of Ukraine, Ternopil, UkraineDepartment of Vitamin and Coenzyme Biochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, UkraineObjectives. The present study was designed to assess whether apoptosis-related genes as parp-1 and bax could be targets for treatment of diabetes mellitus and whether vitamin D may exert beneficial effects.https://doi.org/10.2478/enr-2021-0008type 1 diabetes mellitusmrna expressionparp-1 genebax genevitamin d3
collection DOAJ
language English
format Article
sources DOAJ
author Kuchmerovska Tamara
Guzyk Mykhailo
Tykhonenko Tetiana
Yanitska Lesya
Pryvrotska Irina
Diakun Kateryna
spellingShingle Kuchmerovska Tamara
Guzyk Mykhailo
Tykhonenko Tetiana
Yanitska Lesya
Pryvrotska Irina
Diakun Kateryna
The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus
Endocrine Regulations
type 1 diabetes mellitus
mrna expression
parp-1 gene
bax gene
vitamin d3
author_facet Kuchmerovska Tamara
Guzyk Mykhailo
Tykhonenko Tetiana
Yanitska Lesya
Pryvrotska Irina
Diakun Kateryna
author_sort Kuchmerovska Tamara
title The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus
title_short The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus
title_full The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus
title_fullStr The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus
title_full_unstemmed The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus
title_sort parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus
publisher Sciendo
series Endocrine Regulations
issn 1336-0329
publishDate 2021-04-01
description Objectives. The present study was designed to assess whether apoptosis-related genes as parp-1 and bax could be targets for treatment of diabetes mellitus and whether vitamin D may exert beneficial effects.
topic type 1 diabetes mellitus
mrna expression
parp-1 gene
bax gene
vitamin d3
url https://doi.org/10.2478/enr-2021-0008
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