Detection of additional primary malignancies: the role of CT and PET/CT combined with multiple percutaneous biopsy

Abstract Objective: To evaluate the imaging findings of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and computed tomography (CT) in patients with additional primary tumors, correlating the results with those of the method used in order to elucidate the d...

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Main Authors: Tiago Kojun Tibana, Rômulo Florêncio Tristão Santos, Adalberto Arão Filho, Bernardo Bacelar, Leticia de Assis Martins, Rafael Oliveira de Souza, Edson Marchiori, Thiago Franchi Nunes
Format: Article
Language:English
Published: Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
Series:Radiologia Brasileira
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842019000300166&lng=en&tlng=en
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spelling doaj-1c6b198a0cd44e65a41a57af8e66eca92020-11-24T21:53:44ZengColégio Brasileiro de Radiologia e Diagnóstico por ImagemRadiologia Brasileira1678-709952316617110.1590/0100-3984.2018.0024S0100-39842019000300166Detection of additional primary malignancies: the role of CT and PET/CT combined with multiple percutaneous biopsyTiago Kojun TibanaRômulo Florêncio Tristão SantosAdalberto Arão FilhoBernardo BacelarLeticia de Assis MartinsRafael Oliveira de SouzaEdson MarchioriThiago Franchi NunesAbstract Objective: To evaluate the imaging findings of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and computed tomography (CT) in patients with additional primary tumors, correlating the results with those of the method used in order to elucidate the diagnosis and of the pathology reports. Materials and Methods: We retrospectively analyzed the medical records, pathology reports and images of 11 patients who underwent CT, 18F-FDG PET/CT, or both. We included patients with at least two tumors, with confirmed distinct histopathological profiles, at different sites. Patients in whom there was no diagnostic confirmation were excluded, as were those in whom the additional lesion was suspected of being a metastasis of the first. Results: New primary malignancies were identified in 11 patients, one new tumor being found in 10 and two new tumors being found in 1. The confirmed sites of the additional malignancies were the lung, kidney, prostate, jejunum, and breast. Single or multiple percutaneous biopsies were performed in 10 patients, and 1 patient underwent a surgical procedure for diagnostic and therapeutic purposes. The tumors were metachronous in 6 cases and synchronous in 5. Conclusion: CT and 18F-FDG PET-CT combined with multiple percutaneous biopsy could facilitate the diagnosis of additional lesions, thus optimizing the treatment and follow-up of the affected patients.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842019000300166&lng=en&tlng=enNeoplasms, second primary/etiologyBiopsy, needle/methodsPositron-emission tomography/methodsTomography, X-ray computed/methodsFluorodeoxyglucose F18
collection DOAJ
language English
format Article
sources DOAJ
author Tiago Kojun Tibana
Rômulo Florêncio Tristão Santos
Adalberto Arão Filho
Bernardo Bacelar
Leticia de Assis Martins
Rafael Oliveira de Souza
Edson Marchiori
Thiago Franchi Nunes
spellingShingle Tiago Kojun Tibana
Rômulo Florêncio Tristão Santos
Adalberto Arão Filho
Bernardo Bacelar
Leticia de Assis Martins
Rafael Oliveira de Souza
Edson Marchiori
Thiago Franchi Nunes
Detection of additional primary malignancies: the role of CT and PET/CT combined with multiple percutaneous biopsy
Radiologia Brasileira
Neoplasms, second primary/etiology
Biopsy, needle/methods
Positron-emission tomography/methods
Tomography, X-ray computed/methods
Fluorodeoxyglucose F18
author_facet Tiago Kojun Tibana
Rômulo Florêncio Tristão Santos
Adalberto Arão Filho
Bernardo Bacelar
Leticia de Assis Martins
Rafael Oliveira de Souza
Edson Marchiori
Thiago Franchi Nunes
author_sort Tiago Kojun Tibana
title Detection of additional primary malignancies: the role of CT and PET/CT combined with multiple percutaneous biopsy
title_short Detection of additional primary malignancies: the role of CT and PET/CT combined with multiple percutaneous biopsy
title_full Detection of additional primary malignancies: the role of CT and PET/CT combined with multiple percutaneous biopsy
title_fullStr Detection of additional primary malignancies: the role of CT and PET/CT combined with multiple percutaneous biopsy
title_full_unstemmed Detection of additional primary malignancies: the role of CT and PET/CT combined with multiple percutaneous biopsy
title_sort detection of additional primary malignancies: the role of ct and pet/ct combined with multiple percutaneous biopsy
publisher Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
series Radiologia Brasileira
issn 1678-7099
description Abstract Objective: To evaluate the imaging findings of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and computed tomography (CT) in patients with additional primary tumors, correlating the results with those of the method used in order to elucidate the diagnosis and of the pathology reports. Materials and Methods: We retrospectively analyzed the medical records, pathology reports and images of 11 patients who underwent CT, 18F-FDG PET/CT, or both. We included patients with at least two tumors, with confirmed distinct histopathological profiles, at different sites. Patients in whom there was no diagnostic confirmation were excluded, as were those in whom the additional lesion was suspected of being a metastasis of the first. Results: New primary malignancies were identified in 11 patients, one new tumor being found in 10 and two new tumors being found in 1. The confirmed sites of the additional malignancies were the lung, kidney, prostate, jejunum, and breast. Single or multiple percutaneous biopsies were performed in 10 patients, and 1 patient underwent a surgical procedure for diagnostic and therapeutic purposes. The tumors were metachronous in 6 cases and synchronous in 5. Conclusion: CT and 18F-FDG PET-CT combined with multiple percutaneous biopsy could facilitate the diagnosis of additional lesions, thus optimizing the treatment and follow-up of the affected patients.
topic Neoplasms, second primary/etiology
Biopsy, needle/methods
Positron-emission tomography/methods
Tomography, X-ray computed/methods
Fluorodeoxyglucose F18
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842019000300166&lng=en&tlng=en
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