Preparation of inclusion complex of praziquantel with 2-hydroxypropyl-β-cyclodextrin and pharmacokinetic property improvement

An inclusion complex of praziquantel with 2-hydroxypropyl-β-cyclodextrin was designed and prepared by an optimized method and the inclusion complex was characterized by infrared absorption spectral, proton NMR spectral and scanning electron image studies. It was shown that the aqueous solubility of...

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Bibliographic Details
Main Authors: Yili Ding, Wutong Cui, Yuchang Pang, Chamakura V.N.S. Vara Prasad, Bingyun Wang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221003221