Synthesis and antiproliferative activity of some A- and B modified D-homo lactone androstane derivatives

An efficient synthesis of several A- and B-modified D-homo lactone androstane derivatives from 3β-hydroxy-17-oxa-D-homoandrost-5-en-16-one (1) is reported. 17-Oxa-Dhomoandrost- 4-ene-3,16-dione (2), obtained by the Oppenauer oxidation of compound 1, was converted via the unstable intermedia...

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Bibliographic Details
Main Authors: Savić Marina P., Penov-Gaši Katarina M., Sakač Marija N., Jakimov Dimitar S., Đurendić Evgenija A.
Format: Article
Language:English
Published: Faculty of Technology, Novi Sad 2013-01-01
Series:Acta Periodica Technologica
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/1450-7188/2013/1450-71881344289S.pdf