Neurotoxic Effect of Ethanolic Extract of Propolis in the Presence of Copper Ions is Mediated through Enhanced Production of ROS and Stimulation of Caspase-3/7 Activity

Neurotoxic Effect of Ethanolic Extract of Propolis in the Presence of Copper Ions is Mediated through Enhanced Production of ROS and Stimulation of Caspase-3/7 Activity

Elevated amounts of copper are considered to be contributing factor in the progression of neurodegenerative diseases as they promote oxidative stress conditions. The aim of our study was to examine the effects of ethanolic extract of propolis (EEP) against copper-induced neuronal damage. In cultured...

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Bibliographic Details
Main Authors:	Vedrana Radovanović, Josipa Vlainić, Nikolina Hanžić, Petra Ukić, Nada Oršolić, Goran Baranović, Maja Jazvinšćak Jembrek
Format:	Article
Language:	English
Published:	MDPI AG 2019-05-01
Series:	Toxins
Subjects:	ethanolic extract of propolis copper toxicity p53 p38 and JNK signaling P19 neurons
Online Access:	https://www.mdpi.com/2072-6651/11/5/273

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