EFFICIENCY OF NEW IMMOBILIZED PROBIOTIC AS A PART OF TREATMENT OF PULMONARY TUBERCULOSIS PATIENTS

• Main Authors: I. V. Belovа, I. V. Solovievа, A. G. Tochilinа, S. F. Bаrbolinа, A. V. Pаvlunin, A. S. Shprykov
• Format: Article
• Language: Russian
• Published: NEW TERRA Publishing House 2017-05-01
• Series: Tuberkulez i Bolezni Lëgkih
• Subjects: pulmonary tuberculosis; microorganism community; dysbiosis; immobilized probiotic
• Online Access: https://www.tibl-journal.com/jour/article/view/1002

The study was conducted in order to evaluate the efficiency of adding immobilized probiotic biologically active food supplement of LB-Complex L to integral treatment of pulmonary tuberculosis. Changes of colon microorganism community in pulmonary tuberculosis patients including those with multiple drug resistance were studied in two groups of patients: receiving only basic treatment and basic treatment with the immobolized probiotic of LB-Complex L as a food supplement. The algorithm of probiotic intake has been offered with the consideration of pharmacodynamics of anti-tuberculosis drugs. The offered algorithm proved to be effective for prevention of disorders in microorganism community, enhancement of adherence to treatment, reduction of frequency, severity and duration of side effects to anti-tuberculosis drugs.