An Expeditious and Greener Synthesis of 2-Aminoimidazoles in Deep Eutectic Solvents

An Expeditious and Greener Synthesis of 2-Aminoimidazoles in Deep Eutectic Solvents

A high-yield one-pot two-step synthesis of 2-aminoimidazoles (2-AI), exploiting an under-air heterocyclodehydration process between α-chloroketones and guanidine derivatives, and using deep eutectic solvents (DESs) as nonconventional, “green” and “innocent” reaction media, has been accomplished succ...

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Bibliographic Details
Main Authors: Martina Capua, Serena Perrone, Filippo Maria Perna, Paola Vitale, Luigino Troisi, Antonio Salomone, Vito Capriati
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Molecules
Subjects:
2-aminoimidazoles
deep eutectic solvents
green chemistry
heterocyclization
guanidines
α-chloroketones
Online Access:http://www.mdpi.com/1420-3049/21/7/924

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