| Summary: | Mineral oil has been used in the treatment of constipation in hemodialysis patients. Edible oils could also be a good option for treating this symptom. Therefore we aimed to investigate the effect of flaxseed and olive oils on constipation of hemodialysis patients. This trial was conducted for 4 weeks. Constipation was diagnosed by Rome III criterion. Thirty six constipated patients (18M, 51.0±12.2 years) were randomized into Mineral oil (MG; n=11), Flaxseed oil (FG; n=11) and Olive oil (OG; n=14) groups. The initial dose of each oil was 4 ml/d and was adjusted as needed. There was no difference in total oil used among groups (150.7±43.7 ml, 165.8±53.3 ml, 144.4±49.5 ml, respectively; p=0.61). The prevalence of each Roma III criterion item was similar among the groups.
MG (%)
OG (%)
FG (%)
0
wk4
0
wk4
0
wk4
Abdominal pain
54.5
27.3
36.4
9.1*
9.1
0
Straining on defecation
30.8
7.7
34.6
11.5*
34.6
15.4
Lumpy or hard stools
32.3
9.7
39.7
12.9
29.0
12.9
Incomplete evacuation
28.1
18.8
43.8
28.1
28.1
18.8
Anorectal obstruction
29.2
12.5
45.8
4.2*
25.0
12.5
Manual maneuvers
25.0
0
50.0
0*
25.0
0
< 3 evacuation/week
36.8
5.3*
31.6
10.5*
31.6
15.8
This preliminary result suggests that olive oil could be a healthy alternative on treatment of constipation in hemodialysis patients.
⁎ p<0.05; 0 vs wk4.
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