NELF potentiates gene transcription in the Drosophila embryo.
A hallmark of genes that are subject to developmental regulation of transcriptional elongation is association of the negative elongation factor NELF with the paused RNA polymerase complex. Here we use a combination of biochemical and genetic experiments to investigate the in vivo function of NELF in...
Main Authors: | Xiaoling Wang, Saiyu Hang, Lisa Prazak, J Peter Gergen |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2901382?pdf=render |
Similar Items
-
The negative elongation factor NELF promotes induced transcriptional response of Drosophila ecdysone-dependent genes
by: Marina Yu. Mazina, et al.
Published: (2021-01-01) -
THE ROLE OF NEGATIVE ELONGATION FACTOR NELF IN THE REGULATION OF HIV TRANSCRIPTION, VIRAL LATENCY AND THE CONTROL OF CELLULAR GENE EXPRESSION
by: Wong, Julian Y.
Published: (2012) -
Dual Control of HIV Transcription Elongation: Virus-Specific Negative Control by NELF-E is Counterbalanced by Positive Transcription Factor P-TEFb
by: Jadlowsky, Julie Kendal
Published: (2009) -
Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2
by: Wiebke Manuela Schulze, et al.
Published: (2017-11-01) -
Defining NELF-E RNA binding in HIV-1 and promoter-proximal pause regions.
by: John M Pagano, et al.
Published: (2014-01-01)