Coincidence detection and bi-directional transmembrane signaling control a bacterial second messenger receptor

Coincidence detection and bi-directional transmembrane signaling control a bacterial second messenger receptor

The second messenger c-di-GMP (or cyclic diguanylate) regulates biofilm formation, a physiological adaptation process in bacteria, via a widely conserved signaling node comprising a prototypical transmembrane receptor for c-di-GMP, LapD, and a cognate periplasmic protease, LapG. Previously, we repor...

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Bibliographic Details
Main Authors: Richard B Cooley, John P O’Donnell, Holger Sondermann
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
biofilm formation
second messenger
membrane protein structure
membrane signaling
Online Access:https://elifesciences.org/articles/21848

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