Efficiency of hypertonic and isotonic seawater solutions in chronic rhinosinusitis

• Main Authors: Josip Čulig, Marcel Leppée, Andrijana Včeva, Davorin Djanic
• Format: Article
• Language: English
• Published: Medical Association of Zenica-Doboj Canton 2010-08-01
• Series: Medicinski Glasnik
• Subjects: seawater solution; chronic rhinosinusitis; hypertonic; isotonic; QoL
• Online Access: http://www.ljkzedo.com.ba/medglasnik/vol72/MG7vol2_05pdf

Aim To compare the efficiency of isotonic and hypertonic seawatersolutions used for nasal lavage and quality of life of the patientswith chronic rhinosinusitis. Methods A random and controlled clinical study was performed. The study included 60 patients with history of chronic rhinosinusitis. At the beginning of the study, each subject was given a Patient Lobook, which needed to be filled ut daily during the 15-day tudy period. There were three visits per each patient during the study. Results Patient Logbook notes showed significant statistical differences inall symptoms in the group of patients using hypertonic seawater solution. However, while the notes showed significant statistical differences in congestion and rhinorrhea, in the group of patients using isotonic seawater solution, other symptoms showed no major changes during the study period. Conclusion Hypertonic seawater solution has been proven to bebetter than isotonic seawater solution in eliminating the symptomsof nasal congestion, rhinorrhea, cough, headache and waking up duringthe night.