The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells
The transcription factor STAT3 is activated inappropriately in 70% of breast cancers, most commonly in triple negative breast cancer (TNBC). Although the transcriptional function of STAT3 is essential for tumorigenesis, the key target genes regulated by STAT3 in driving tumor pathogenesis have remai...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-05-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558618300113 |