The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells

The transcription factor STAT3 is activated inappropriately in 70% of breast cancers, most commonly in triple negative breast cancer (TNBC). Although the transcriptional function of STAT3 is essential for tumorigenesis, the key target genes regulated by STAT3 in driving tumor pathogenesis have remai...

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Bibliographic Details
Main Authors: Susana P. Egusquiaguirre, Jennifer E. Yeh, Sarah R. Walker, Suhu Liu, David A. Frank
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558618300113