<i>In vitro</i> Production and Immunogenicity of a <i>Clostridium Difficile</i> Spore-Specific BclA3 Glycopeptide Conjugate Vaccine

<i>In vitro</i> Production and Immunogenicity of a <i>Clostridium Difficile</i> Spore-Specific BclA3 Glycopeptide Conjugate Vaccine

<b>A</b><b>bstract: </b>The BclA3 glycoprotein is a major component of the exosporangial layer of <i>Clostridium difficile</i> spores and in this study we demonstrate that this glycoprotein is a major spore surface associated antigen. Here, we confirm the role of...

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Bibliographic Details
Main Authors: Annie Aubry, Wei Zou, Evguenii Vinogradov, Dean Williams, Wangxue Chen, Greg Harris, Hongyan Zhou, Melissa J. Schur, Michel Gilbert, Gillian R. Douce, Susan M. Logan
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Vaccines
Subjects:
<i>c. difficile</i> vaccine
bcla3 spore glycoprotein
o-glcnac transferase
glycopeptide
conjugate
immunogenicity
Online Access:https://www.mdpi.com/2076-393X/8/1/73

Internet

https://www.mdpi.com/2076-393X/8/1/73

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