Dietary Exposure Assessment of Veterinary Antibiotics in Pork Meat on Children and Adolescents in Cyprus

In recent years, huge amounts of antibiotics have been administered to farm animals, and as a result, residues of these antibiotics can accumulate in livestock products and, once consumed, may be transmitted to humans. Farm animals’ antibiotic treatment may therefore present a risk for consumers hea...

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Main Authors: Demetra Kyriakides, Andreas C. Lazaris, Konstantinos Arsenoglou, Maria Emmanouil, Olympia Kyriakides, Nikolaos Kavantzas, Irene Panderi
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/9/10/1479
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spelling doaj-1c1256b84df94a2b866be20bc5c03fee2020-11-25T03:52:07ZengMDPI AGFoods2304-81582020-10-0191479147910.3390/foods9101479Dietary Exposure Assessment of Veterinary Antibiotics in Pork Meat on Children and Adolescents in CyprusDemetra Kyriakides0Andreas C. Lazaris1Konstantinos Arsenoglou2Maria Emmanouil3Olympia Kyriakides4Nikolaos Kavantzas5Irene Panderi6Laboratory of Pathological Anatomy, Department of Clinical and Laboratory Medicine, School of Medicine, National and Kapodistrian University of Athens, 75, Mikras Asias Avenue, Goudi, 11527 Athens, GreeceLaboratory of Pathological Anatomy, Department of Clinical and Laboratory Medicine, School of Medicine, National and Kapodistrian University of Athens, 75, Mikras Asias Avenue, Goudi, 11527 Athens, GreeceVeterinary Services, Ministry of Agriculture, Rural Development and Environment, 1417 Nicosia, CyprusVeterinary Services, Ministry of Agriculture, Rural Development and Environment, 1417 Nicosia, CyprusArchbishop Makarios III Hospital, 2012 Nicosia, CyprusLaboratory of Pathological Anatomy, Department of Clinical and Laboratory Medicine, School of Medicine, National and Kapodistrian University of Athens, 75, Mikras Asias Avenue, Goudi, 11527 Athens, GreeceLaboratory of Pharmaceutical Analysis, Panepistimiopolis, Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Zografou, 15771 Athens, GreeceIn recent years, huge amounts of antibiotics have been administered to farm animals, and as a result, residues of these antibiotics can accumulate in livestock products and, once consumed, may be transmitted to humans. Farm animals’ antibiotic treatment may therefore present a risk for consumers health, especially for children and adolescents. In children, the immune system is not fully developed, and thus, they are more susceptible than adults to resistant bacteria. A dietary exposure assessment was conducted on veterinary antibiotics found in raw pork meat among children and adolescents in Cyprus, since pork is the most consumed red meat in Cypriot population. The study was based on the results of the occurrence of 45 residual antibiotics in raw pork meat samples in Cyprus between 2012 and 2017 in combination with data on the consumption of pork meat on children and adolescents taken from the latest demographic report in Cyprus. Estimated daily intake (EDI) values of veterinary antibiotics for children aged 6–9 years old, were higher compared to EDI values for adolescents aged 10–17 years old. The percentage ratio of the estimated daily intake to the acceptable daily intake for all the veterinary antibiotic residues was less than 5.6. The results indicate that antibiotic residues in pork meat of inland production are below the acceptable daily intake and are of low risk to human health related to the exposure of antibiotics. Nevertheless, continuous exposure to low levels of antibiotic residues in respect to age vulnerability should be of a great concern.https://www.mdpi.com/2304-8158/9/10/1479food compositionveterinary antibioticsdietary exposure assessmentchildadolescentpork meat
collection DOAJ
language English
format Article
sources DOAJ
author Demetra Kyriakides
Andreas C. Lazaris
Konstantinos Arsenoglou
Maria Emmanouil
Olympia Kyriakides
Nikolaos Kavantzas
Irene Panderi
spellingShingle Demetra Kyriakides
Andreas C. Lazaris
Konstantinos Arsenoglou
Maria Emmanouil
Olympia Kyriakides
Nikolaos Kavantzas
Irene Panderi
Dietary Exposure Assessment of Veterinary Antibiotics in Pork Meat on Children and Adolescents in Cyprus
Foods
food composition
veterinary antibiotics
dietary exposure assessment
child
adolescent
pork meat
author_facet Demetra Kyriakides
Andreas C. Lazaris
Konstantinos Arsenoglou
Maria Emmanouil
Olympia Kyriakides
Nikolaos Kavantzas
Irene Panderi
author_sort Demetra Kyriakides
title Dietary Exposure Assessment of Veterinary Antibiotics in Pork Meat on Children and Adolescents in Cyprus
title_short Dietary Exposure Assessment of Veterinary Antibiotics in Pork Meat on Children and Adolescents in Cyprus
title_full Dietary Exposure Assessment of Veterinary Antibiotics in Pork Meat on Children and Adolescents in Cyprus
title_fullStr Dietary Exposure Assessment of Veterinary Antibiotics in Pork Meat on Children and Adolescents in Cyprus
title_full_unstemmed Dietary Exposure Assessment of Veterinary Antibiotics in Pork Meat on Children and Adolescents in Cyprus
title_sort dietary exposure assessment of veterinary antibiotics in pork meat on children and adolescents in cyprus
publisher MDPI AG
series Foods
issn 2304-8158
publishDate 2020-10-01
description In recent years, huge amounts of antibiotics have been administered to farm animals, and as a result, residues of these antibiotics can accumulate in livestock products and, once consumed, may be transmitted to humans. Farm animals’ antibiotic treatment may therefore present a risk for consumers health, especially for children and adolescents. In children, the immune system is not fully developed, and thus, they are more susceptible than adults to resistant bacteria. A dietary exposure assessment was conducted on veterinary antibiotics found in raw pork meat among children and adolescents in Cyprus, since pork is the most consumed red meat in Cypriot population. The study was based on the results of the occurrence of 45 residual antibiotics in raw pork meat samples in Cyprus between 2012 and 2017 in combination with data on the consumption of pork meat on children and adolescents taken from the latest demographic report in Cyprus. Estimated daily intake (EDI) values of veterinary antibiotics for children aged 6–9 years old, were higher compared to EDI values for adolescents aged 10–17 years old. The percentage ratio of the estimated daily intake to the acceptable daily intake for all the veterinary antibiotic residues was less than 5.6. The results indicate that antibiotic residues in pork meat of inland production are below the acceptable daily intake and are of low risk to human health related to the exposure of antibiotics. Nevertheless, continuous exposure to low levels of antibiotic residues in respect to age vulnerability should be of a great concern.
topic food composition
veterinary antibiotics
dietary exposure assessment
child
adolescent
pork meat
url https://www.mdpi.com/2304-8158/9/10/1479
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