A microtubule-based minimal model for spontaneous and persistent spherical cell polarity.

We propose a minimal model for the spontaneous and persistent generation of polarity in a spherical cell based on dynamic microtubules and a single mobile molecular component. This component, dubbed the polarity factor, binds to microtubules nucleated from a centrosome located in the center of the c...

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Bibliographic Details
Main Authors: Panayiotis Foteinopoulos, Bela M Mulder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5607169?pdf=render