Epigenetically inactivated RASSF1A as a tumor biomarker
RASSF1A represents one of the eight isoforms of the RASSF1 gene. RASSF1A is a tumor suppressor gene whose inactivation influences tumor initiation and development. In cancer, RASSF1A is frequently inactivated by mutations, loss of heterozygosity and, most commonly, by promoter hypermethylation. As...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2020-11-01
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Series: | Bosnian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/5219 |