Targeting of M2-like tumor-associated macrophages with a melittin-based pro-apoptotic peptide

Targeting of M2-like tumor-associated macrophages with a melittin-based pro-apoptotic peptide

Abstract Background Tumor-associated macrophages (TAMs) are the major component of tumor-infiltrating immune cells. Macrophages are broadly categorized as M1 or M2 types, and TAMs have been shown to express an M2-like phenotype. TAMs promote tumor progression and contribute to resistance to chemothe...

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Bibliographic Details
Main Authors: Chanju Lee, Hyunju Jeong, Younghyeon Bae, Kyungmoon Shin, Sinwoo Kang, Hwikyung Kim, Jayoung Oh, Hyunsu Bae
Format: Article
Language:English
Published: BMJ Publishing Group 2019-06-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Tumor-associated macrophages
Melittin
Pro-apoptotic peptide
Cancer immunotherapy
Therapeutic agent
Online Access:http://link.springer.com/article/10.1186/s40425-019-0610-4

Internet

http://link.springer.com/article/10.1186/s40425-019-0610-4

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