Single‐channel EEG classification of sleep stages based on REM microstructure

• Main Authors: Irene Rechichi, Maurizio Zibetti, Luigi Borzì, Gabriella Olmo, Leonardo Lopiano
• Format: Article
• Language: English
• Published: Wiley 2021-06-01
• Series: Healthcare Technology Letters
• Online Access: https://doi.org/10.1049/htl2.12007

Abstract Rapid‐eye movement (REM) sleep, or paradoxical sleep, accounts for 20–25% of total night‐time sleep in healthy adults and may be related, in pathological cases, to parasomnias. A large percentage of Parkinson's disease patients suffer from sleep disorders, including REM sleep behaviour disorder and hypokinesia; monitoring their sleep cycle and related activities would help to improve their quality of life. There is a need to accurately classify REM and the other stages of sleep in order to properly identify and monitor parasomnias. This study proposes a method for the identification of REM sleep from raw single‐channel electroencephalogram data, employing novel features based on REM microstructures. Sleep stage classification was performed by means of random forest (RF) classifier, K‐nearest neighbour (K‐NN) classifier and random Under sampling boosted trees (RUSBoost); the classifiers were trained using a set of published and novel features. REM detection accuracy ranges from 89% to 92.7%, and the classifiers achieved a F‐1 score (REM class) of about 0.83 (RF), 0.80 (K‐NN), and 0.70 (RUSBoost). These methods provide encouraging outcomes in automatic sleep scoring and REM detection based on raw single‐channel electroencephalogram, assessing the feasibility of a home sleep monitoring device with fewer channels.