Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases

Rapid eye movement sleep behavior disorder (RBD) is a sleep disorder characterized by the disappearance of muscle relaxation and enacting one's dreams during rapid eye movement (REM), with most of the dreams being violent or aggressive. Prevalence of RBD, based on population, is 0.38%-2.01%, bu...

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Main Authors:	Hai-yang JIANG, Jin-sha HUANG, Tao WANG
Format:	Article
Language:	English
Published:	Tianjin Huanhu Hospital 2017-10-01
Series:	Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:	REM sleep behavior disorder Neurodegenerative diseases Review
Online Access:	http://www.cjcnn.org/index.php/cjcnn/article/view/1671

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spelling	doaj-1bf72421da12472eadd7664b78cd8b442020-11-25T02:09:37ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312017-10-0117107177221633Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseasesHai-yang JIANG0Jin-sha HUANG1Tao WANG2Department of Neurology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing Medical University, Nanjing 210008, Jiangsu, ChinaDepartment of Neurology, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, ChinaDepartment of Neurology, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, ChinaRapid eye movement sleep behavior disorder (RBD) is a sleep disorder characterized by the disappearance of muscle relaxation and enacting one's dreams during rapid eye movement (REM), with most of the dreams being violent or aggressive. Prevalence of RBD, based on population, is 0.38%-2.01%, but it becomes much higher in patients with neurodegenerative diseases, especially α - synucleinopathies. RBD may herald the emergence of α-synucleinopathies by decades, thus it may be used as an effective early marker of neurodegenerative diseases. In this review, we summarized the progress on the pathogenesis of RBD and its relationship with neurodegenerative diseases. DOI: 10.3969/j.issn.1672-6731.2017.10.003http://www.cjcnn.org/index.php/cjcnn/article/view/1671REM sleep behavior disorderNeurodegenerative diseasesReview
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Hai-yang JIANG Jin-sha HUANG Tao WANG
spellingShingle	Hai-yang JIANG Jin-sha HUANG Tao WANG Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases Chinese Journal of Contemporary Neurology and Neurosurgery REM sleep behavior disorder Neurodegenerative diseases Review
author_facet	Hai-yang JIANG Jin-sha HUANG Tao WANG
author_sort	Hai-yang JIANG
title	Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases
title_short	Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases
title_full	Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases
title_fullStr	Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases
title_full_unstemmed	Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases
title_sort	research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases
publisher	Tianjin Huanhu Hospital
series	Chinese Journal of Contemporary Neurology and Neurosurgery
issn	1672-6731
publishDate	2017-10-01
description	Rapid eye movement sleep behavior disorder (RBD) is a sleep disorder characterized by the disappearance of muscle relaxation and enacting one's dreams during rapid eye movement (REM), with most of the dreams being violent or aggressive. Prevalence of RBD, based on population, is 0.38%-2.01%, but it becomes much higher in patients with neurodegenerative diseases, especially α - synucleinopathies. RBD may herald the emergence of α-synucleinopathies by decades, thus it may be used as an effective early marker of neurodegenerative diseases. In this review, we summarized the progress on the pathogenesis of RBD and its relationship with neurodegenerative diseases. DOI: 10.3969/j.issn.1672-6731.2017.10.003
topic	REM sleep behavior disorder Neurodegenerative diseases Review
url	http://www.cjcnn.org/index.php/cjcnn/article/view/1671
work_keys_str_mv	AT haiyangjiang researchprogressonthepathogenesisofrapideyemovementsleepbehaviordisorderandneurodegenerativediseases AT jinshahuang researchprogressonthepathogenesisofrapideyemovementsleepbehaviordisorderandneurodegenerativediseases AT taowang researchprogressonthepathogenesisofrapideyemovementsleepbehaviordisorderandneurodegenerativediseases
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Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases

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