Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases

Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases

Rapid eye movement sleep behavior disorder (RBD) is a sleep disorder characterized by the disappearance of muscle relaxation and enacting one's dreams during rapid eye movement (REM), with most of the dreams being violent or aggressive. Prevalence of RBD, based on population, is 0.38%-2.01%, bu...

Full description

Bibliographic Details
Main Authors: Hai-yang JIANG, Jin-sha HUANG, Tao WANG
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2017-10-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
REM sleep behavior disorder
Neurodegenerative diseases
Review
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/1671
Description
Summary:Rapid eye movement sleep behavior disorder (RBD) is a sleep disorder characterized by the disappearance of muscle relaxation and enacting one's dreams during rapid eye movement (REM), with most of the dreams being violent or aggressive. Prevalence of RBD, based on population, is 0.38%-2.01%, but it becomes much higher in patients with neurodegenerative diseases, especially α - synucleinopathies. RBD may herald the emergence of α-synucleinopathies by decades, thus it may be used as an effective early marker of neurodegenerative diseases. In this review, we summarized the progress on the pathogenesis of RBD and its relationship with neurodegenerative diseases. DOI: 10.3969/j.issn.1672-6731.2017.10.003
ISSN:1672-6731

Similar Items