Effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section

• Main Author: Hong Deng
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2017-06-01
• Series: Journal of Hainan Medical University
• Subjects: serum oxidative stress indexes ROS and MDA levels of observation group were significantly lower than those of control group while SOD; GSH-px and CAT levels were significantly higher than those of control group; and serum stress hormones NE; E and Cor levels were significantly lower than those of control group. Conclusion: Hemabate combined with packing therapy can effectively reduce systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section; Placenta previa Cesarean section Postpartum hemorrhage Hemabate Stress
• Online Access: http://www.hnykdxxb.com/PDF/201712/18.pdf
• ISSN: 1007-1237; 1007-1237

Objective: To discuss the effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section. Methods: 70 patients with postpartum hemorrhage after placenta previa cesarean section who were treated in Chengdu Women & Children’s Central Hospital between January 2014 and February 2017 were collected and then divided into the control group (n=35) who received uterine packing therapy and the observation group (n=35) who received Hemabate combined with packing therapy according to random number table. Serum levels of oxidative stress indexes and stress hormones immediately after operation and 24 h after operation were compared between two groups of patients. Results: Immediately after operation and 24 h after operation, serum oxidative stress indexes ROS and MDA levels of observation group were significantly lower than those of control group while SOD, GSH-px and CAT levels were significantly higher than those of control group, and serum stress hormones NE, E and Cor levels were significantly lower than those of control group. Conclusion: Hemabate combined with packing therapy can effectively reduce systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section, is a more ideal way of the bleeding.