High-resolution positron emission microscopy of patient-derived tumor organoids

Positron emission tomography (PET) radiotracers measure the metabolic activity in cancer cells in patients. Here, the authors develop a microscopy method to image organoids using clinical radiotracers, which allows a direct comparison to PET imaging in patients.

Bibliographic Details
Main Authors:	Syamantak Khan, June Ho Shin, Valentina Ferri, Ning Cheng, Julia E. Noel, Calvin Kuo, John B. Sunwoo, Guillem Pratx
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-10-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-021-26081-6

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spelling	doaj-1bf0a70df6824a0da908acd2def55fbf2021-10-10T11:46:15ZengNature Publishing GroupNature Communications2041-17232021-10-0112111110.1038/s41467-021-26081-6High-resolution positron emission microscopy of patient-derived tumor organoidsSyamantak Khan0June Ho Shin1Valentina Ferri2Ning Cheng3Julia E. Noel4Calvin Kuo5John B. Sunwoo6Guillem Pratx7Department of Radiation Oncology, Division of Medical Physics, Stanford University School of MedicineDepartment of Otolaryngology, Division of Head and Neck Surgery, Stanford University School of MedicineDepartment of Radiology, Division of Nuclear Medicine and Molecular Imaging, Stanford University School of MedicineDivision of Hematology, Department of Medicine, Stanford University School of MedicineDepartment of Otolaryngology, Division of Head and Neck Surgery, Stanford University School of MedicineDivision of Hematology, Department of Medicine, Stanford University School of MedicineDepartment of Otolaryngology, Division of Head and Neck Surgery, Stanford University School of MedicineDepartment of Radiation Oncology, Division of Medical Physics, Stanford University School of MedicinePositron emission tomography (PET) radiotracers measure the metabolic activity in cancer cells in patients. Here, the authors develop a microscopy method to image organoids using clinical radiotracers, which allows a direct comparison to PET imaging in patients.https://doi.org/10.1038/s41467-021-26081-6
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Syamantak Khan June Ho Shin Valentina Ferri Ning Cheng Julia E. Noel Calvin Kuo John B. Sunwoo Guillem Pratx
spellingShingle	Syamantak Khan June Ho Shin Valentina Ferri Ning Cheng Julia E. Noel Calvin Kuo John B. Sunwoo Guillem Pratx High-resolution positron emission microscopy of patient-derived tumor organoids Nature Communications
author_facet	Syamantak Khan June Ho Shin Valentina Ferri Ning Cheng Julia E. Noel Calvin Kuo John B. Sunwoo Guillem Pratx
author_sort	Syamantak Khan
title	High-resolution positron emission microscopy of patient-derived tumor organoids
title_short	High-resolution positron emission microscopy of patient-derived tumor organoids
title_full	High-resolution positron emission microscopy of patient-derived tumor organoids
title_fullStr	High-resolution positron emission microscopy of patient-derived tumor organoids
title_full_unstemmed	High-resolution positron emission microscopy of patient-derived tumor organoids
title_sort	high-resolution positron emission microscopy of patient-derived tumor organoids
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2021-10-01
description	Positron emission tomography (PET) radiotracers measure the metabolic activity in cancer cells in patients. Here, the authors develop a microscopy method to image organoids using clinical radiotracers, which allows a direct comparison to PET imaging in patients.
url	https://doi.org/10.1038/s41467-021-26081-6
work_keys_str_mv	AT syamantakkhan highresolutionpositronemissionmicroscopyofpatientderivedtumororganoids AT junehoshin highresolutionpositronemissionmicroscopyofpatientderivedtumororganoids AT valentinaferri highresolutionpositronemissionmicroscopyofpatientderivedtumororganoids AT ningcheng highresolutionpositronemissionmicroscopyofpatientderivedtumororganoids AT juliaenoel highresolutionpositronemissionmicroscopyofpatientderivedtumororganoids AT calvinkuo highresolutionpositronemissionmicroscopyofpatientderivedtumororganoids AT johnbsunwoo highresolutionpositronemissionmicroscopyofpatientderivedtumororganoids AT guillempratx highresolutionpositronemissionmicroscopyofpatientderivedtumororganoids
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High-resolution positron emission microscopy of patient-derived tumor organoids

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