Integrating Network Pharmacology and RT-qPCR Analysis to Investigate the Mechanisms Underlying ZeXie Decoction-Mediated Treatment of Non-alcoholic Fatty Liver Disease

Integrating Network Pharmacology and RT-qPCR Analysis to Investigate the Mechanisms Underlying ZeXie Decoction-Mediated Treatment of Non-alcoholic Fatty Liver Disease

ZeXie Decoction (ZXD) is a traditional Chinese medicine composed of Alisma orientalis (Sam.) Juzep. and Atractylodes macrocephala Koidz. ZXD has been widely used to treat non-alcoholic fatty liver disease (NAFLD). The mechanistic basis for the pharmacological activity of ZXD, however, remains poorly...

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Bibliographic Details
Main Authors: Jiashuo Wu, Fangqing Zhang, Haonan Ruan, Xiaoyan Chang, Jingxun Wang, Zhuangzhuang Li, Weiyi Jin, Yue Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
ZeXie decoction
network pharmacology
RT-qPCR analysis
non-alcoholic fatty liver disease
integrating strategy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.722016/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.722016/full

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