Brain and Plasma Riluzole Pharmacokinetics: Effect of Minocycline Combination
PURPOSE: amyotrophic lateral sclerosis is a fatal neurodegenerative disease characterized by the loss of motorneurons. The only drug approved is riluzole. Minocycline is an antibiotic with numerous neuroprotective properties. riluzole and minocycline were given to an animal model of ALS and had bene...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Canadian Society for Pharmaceutical Sciences
2009-08-01
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Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/4596 |