Kinesin and dynein use distinct mechanisms to bypass obstacles

Kinesin-1 and cytoplasmic dynein are microtubule (MT) motors that transport intracellular cargoes. It remains unclear how these motors move along MTs densely coated with obstacles of various sizes in the cytoplasm. Here, we tested the ability of single and multiple motors to bypass synthetic obstacl...

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Bibliographic Details
Main Authors: Luke S Ferro, Sinan Can, Meghan A Turner, Mohamed M ElShenawy, Ahmet Yildiz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/48629