Kinesin and dynein use distinct mechanisms to bypass obstacles
Kinesin-1 and cytoplasmic dynein are microtubule (MT) motors that transport intracellular cargoes. It remains unclear how these motors move along MTs densely coated with obstacles of various sizes in the cytoplasm. Here, we tested the ability of single and multiple motors to bypass synthetic obstacl...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/48629 |